Abstract: Nursing work is an integral part of hospital work. Under the challenge of the COVID-19 epidemic, it is particularly important to establish a timely and efficient nursing management system. The nursing department of our hospital used the theory and method of feedforward control to formulate the emergency plan for epidemic prevention and control and to conduct drills. The plan includes the establishment of the emergency management system for epidemic nursing and key prevention and control positions, rational allocation of human resources, and strengthening personnel training, so as to ensure the efficient operation of nursing epidemic prevention and control work and provide a reference for nursing management mode during the epidemic.