Abstract: Core body temperature (CBT) is increasingly attracting attention as crucial data during target temperature management (TTM). Accurate and continuous measurement of human CBT can effectively identify and monitor central high fever, and provide a basis for the effective implementation during TTM, which is therefore of great significance for human health care and disease monitoring. The reliable core measurement sites are nasopharynx, esophagus, bladder, rectum, pulmonary artery, etc., but the measurement methods in these sites are all invasive. At present, the medical field is more inclined to noninvasive data collection methods through monitoring an appropriate site (such as forehead, mouth, or axilla) depending on clinical circumstances, so as to ensure the comfort and security of patients to the greatest extent. This review will provide reference choosing more safe and accurate temperature measurement methods for patients during TTM by reviewing the sites and accuracy of invasive and noninvasive CBT measurements.

Key words: Core body temperature, neurocritical care, target temperature management